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Been experimenting with stacking NMN and NR together for the past six months and honestly the combined benefits on my NAD+ levels has been incredible - I take 750mg of each with breakfast and my energy levels feel like they've returned to my prime years, plus my healthcare provider confirmed my blood markers show significant improvement in glucose regulation and the combination seems to be more effective than either nicotinamide mononucleotide or nicotinamide riboside alone since they target different absorption routes with NMN using the Slc12a8 transporter while NR goes through the salvage pathway so you're essentially hitting different mechanisms of NAD+ restoration which is essential for SIRT1 function, PARP enzyme support, and fighting the natural NAD+ decline with age that starts around middle age - definitely recommend adding quercetin as a CD38 enzyme inhibitor to minimize NAD+ degradation and maybe some TMG for metabolic balance.

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