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JayneCawth

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Registered: 2026-06-18

Posts: 6

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Has anyone tried combining both NMN and NR for maximum NAD+ increase?

Great discussion topic! I've been exploring nicotinamide mononucleotide and nicotinamide riboside for several months now and the evidence suggests is that stacking NMN NR together can significantly restore NAD+ levels through various mechanisms - nicotinamide mononucleotide works through the Slc12a8 transporter while nicotinamide riboside works via NRK1 NRK2 enzymes and both boost mitochondrial function plus longevity pathways which is crucial for healthy aging especially since NAD+ levels drop as we age starts in our thirties and combining them with quercetin CD38 inhibitor and TMG methylation support has enhanced my mitochondrial energy and mental clarity significantly - I'm currently using moderate doses of each in my daily stack

Here is my blog: cellular health optimization - help.alternative-erp.com -